Interview with Professor Luis Andrade: ICAP 2019 – what’s new?

Five years ago, the ICAP initiative on harmonisation and standardisation in the nomenclature of HEp-2 IFA patterns was implemented at the International Workshop on Autoantibodies and Autoimmunity (IWAA) in São Paulo, Brazil. Luis E. C. Andrade, professor at the Rheumatology Division, Escola Paulista de Medicina, Universidade Federal de São Paulo, has been involved from the […]


Guidelines for diagnosis and therapy of ANCA-associated vasculitides

In December 2017, the German Society for Rheumatology (DGRh) published their first guideline for the diagnosis and treatment of ANCA-associated forms of vasculitis (AAV) [1]. The AAV encompass granulomatosis with polyangiitis (GPA, formerly Wegener’s granulomatosis), microscopic polyangiitis (MPA) and eosinophilic granulomatosis with polyangiitis (EGPA, formerly Churg-Strauss syndrome), which all occur with autoantibodies against cytoplasmic antigens


EUVAS study confirms efficiency of automated multiparametric immunofluorescene for detection of vasculitis-associated ANCA

Scientist of the European Vasculitis Study (EUVAS) group published the results of a recent study (Csernok et al., Autoimmunity Reviews 2016) testing the performance of two fully automated platforms for multiparametric ANCA IIFT diagnostics which combine cell substrates and monospecific antigen substrates: the EUROPLUS Granulocyte Mosaic (EUROPattern, Euroimmun AG) and CytoBead ANCA (Aklides, Medipan/Generic Assays


23 at one swoop

Using the EUROLINE ANA Profil 23 a patient sample can be tested for autoantibodies against 23 different nuclear antigens in one incubation. They are considered as the most important antigens which underlie the nuclear ANA patterns defined by an international consensus. For more than 50 years the abbreviation “ANA” has been used to describe anti-nuclear antibodies which

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