Using the EUROLINE ANA Profil 23 a patient sample can be tested for autoantibodies against 23 different nuclear antigens in one incubation. They are considered as the most important antigens which underlie the nuclear ANA patterns defined by an international consensus. For more than 50 years the abbreviation “ANA” has been used to describe anti-nuclear antibodies which […]
Dengue fever is spreading rapidly worldwide. The map displays the high number of countries which are threatened by dengue to date. Even in Europe, the number of infected persons increases every year. They have caught the responsible dengue virus (DENV) during vacation in tropical or subtropical countries. The virus is transmitted to humans by a mosquito bite. Dengue fever is
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease which causes severe damage to the joints and leads to serious mobility impairment in the affected persons. RA cannot be cured, but can nowadays be treated, if diagnosed on time. In contrast to rheumatoid factors (RF), antibodies against the so-called citrullinated peptides (anti-citrullinated peptide antibodies, ACPA)
Clinicians and biologists expect increasing numbers of infections with hantaviruses in Germany this year due to the ongoing strong reproduction of the bank vole and the striped field mouse. The rodents function as reservoirs and spread the virus through their excrements. Dust, contaminated with the pathogen, may be inhaled by humans when sweeping a shed
There are diseases whose pathogenesis has been known for decades. The actual cause, however, remains a secret despite intensive research. For decades, it has been known that deposits of immune complexes are formed along the basal membrane of the glomerulus in membranous nephropathy (previously known as membranous glomerulonephritits), causing tissue inflammation and impairment of kidney filtration. But the antigen which is targeted by
