Science

UNIQO 160 – from primary sample to final result

The UNIQO 160 embodies the next generation of fully automated systems for indirect immunofluorescence diagnostics. What is behind it? After the fully automated processing of the indirect immunofluorescence tests (IIFT), the system automatically covers the incubated slides with mounting medium to protect the slides from drying out. This alone is a special feature among fully […]

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Novel autoantibody against septin-3 discovered in neurological disease

The cytoskeleton protein septin-3 has been identified as a novel target antigen of autoantibodies in patients with paraneoplastic cerebellar ataxia. The new biomarker was discovered in a collaborative study between scientists at EUROIMMUN, the University of Heidelberg and further clinics in Germany. Septins are cytoskeletal proteins with multiple roles in cell division, cellular polarisation, morphogenesis

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Computer-aided classification of IIF patterns in autoimmune dermatoses

Deep neural networks incorporating segmentation provide highly accurate classification of immunofluorescence patterns on the tissue substrates esophagus and salt-split skin for detection of autoimmune bullous dermatoses (AIBD). A recently published study in collaboration with researchers at the Department of Dermatology and Lübeck Institute of Experimental Dermatology of the University of Lübeck, Germany describes the development

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Indirect immunofluorescence microscopy using our IVDR-compliant EUROStar III Plus

Microscopy is a fundamental tool in biomedical research and clinical diagnostics. However, each laboratory has different requirements for its instruments: While laboratories with a low sample throughput tend to use manual microscopes, for example for the evaluation of indirect immunofluorescence tests, large laboratories with a high throughput and a broad diagnostic spectrum rather benefit from

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Recombinant ELISAs increase efficiency of CMV serodiagnosis in pregnant women

EUROIMMUN ELISAs based on recombinant antigens p52 (IgM) and glycoprotein B (IgG) from cytomegalovirus (CMV) provided a higher rate of conclusive results in first-line testing of samples from pregnant women than lysate-based assays. A recombinant testing strategy could thus help to reduce the number of analyses required for routine CMV screening during pregnancy. These are

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