When antibodies of class IgE against the peanut proteins Ara h2 and Ara h6 are detected in a patient sample, this finding points with high probability to a clinical peanut allergy. After eating a peanut, the binding between IgE antibodies and their target proteins leads to the activation of mast cells. The activated immune cells […]
Measles and mumps, two forgotten diseases, reveal an unfortunate comeback. In a free webinar, Oliver Sendscheid, PhD, Scientific Director at EUROIMMUN US, and Rolando Pajon, PhD, Lead Scientist for Vaccine and Novel Immunotherapeutic Laboratory Solutions at COVANCE CLS address the current epidemiologic status of measles and mumps, challenges and solutions in serological testing, perspectives in vaccine
Approximately every fifth person in Europe and almost all adults in large parts of Asia are not able to digest lactose. This is referred to as lactose intolerance. Actually, lactose intolerance is not a disease, but the natural state in mammals. After weaning, the activity of the digestive enzyme lactase, which splits lactose into the
In December 2017, the German Society for Rheumatology (DGRh) published their first guideline for the diagnosis and treatment of ANCA-associated forms of vasculitis (AAV) [1]. The AAV encompass granulomatosis with polyangiitis (GPA, formerly Wegener’s granulomatosis), microscopic polyangiitis (MPA) and eosinophilic granulomatosis with polyangiitis (EGPA, formerly Churg-Strauss syndrome), which all occur with autoantibodies against cytoplasmic antigens
In persons with type I allergies, the immune system forms IgE antibodies at first contact with a usually harmless substance (allergen) from the environment, e.g. against certain proteins in pollen, animal hair or food. At every further contact, the binding between the antibodies and the allergen can cause diverse immune reactions, including swelling of mucous
