Bullous pemphigoid (BP) is considered the most frequent autoimmune blistering disease with an incidence of about 1.5 to 2 per 100,000 inhabitants and year in the general population. The disease becomes even more frequent in the elderly. The clinical picture…
Read more
Autoimmune-mediated damage to the kidneys can be triggered by autoantibodies directed against renal proteins, as in the case of primary membranous nephropathy (MN) or Goodpasture syndrome, or may occur secondary as part of the wide-reaching effects of systemic autoimmune diseases…
Read more
Bone metabolic diseases are a major health problem, causing bone fractures, skeletal pain and deformities. Bone tissue is a living tissue which is composed of c…
The skin is considered the largest and most versatile organ of the human organism. It hinders pathogens and harmful substances from entering the body, protects…
Uromodulin is a kidney-specific glycoprotein, which is mainly secreted in the urine but also, in small amounts, into the bloodstream. Since it was discovered se…
Uromodulin is a kidney-specific glycoprotein, which is exclusively expressed by the epithelial cells of the ascending limb of loop of Henle (TAL cells) and secr…