Science

Ara h7: A novel major peanut allergen

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When antibodies of class IgE against the peanut proteins Ara h2 and Ara h6 are detected in a patient sample, this finding points with high probability to a clinical peanut allergy. After eating a peanut, the binding between IgE antibodies and their target proteins leads to the activation of mast cells. The activated immune cells […]

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Cross-reactive anti-CCD antibodies can hinder allergy diagnostics

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In persons with type I allergies, the immune system forms IgE antibodies at first contact with a usually harmless substance (allergen) from the environment, e.g. against certain proteins in pollen, animal hair or food. At every further contact, the binding between the antibodies and the allergen can cause diverse immune reactions, including swelling of mucous

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