Circulating uromodulin may help identify kidney dysfunction in sickle cell disease while conventional kidney markers remain within reference range, as demonstrated in a recent collaborative study conducted with Euroimmun, University Hospital Essen, Germany and other academic and clinical partners.   A diagnostic challenge Sickle cell nephropathy is a major cause of illness and early death […]

A collaborative study with Euroimmun, published recently in the journal Brain, has identified septin multimer as a novel target of autoimmunity in patients with severe motor neuropathy. The autoantibodies may represent a new biomarker for a rare but clinically significant disease subgroup.   What are septins? Septins are a family of ubiquitously expressed cytoskeletal proteins

Identifying autoimmune encephalitis (AIE) in patients with psychiatric symptoms is challenging, especially since many associated autoantibodies are rare and not routinely tested. A recent case study of steroid-responsive psychosis linked to anti-septin-7 antibodies — characterised in collaboration with Euroimmun and published in Translational Psychiatry — highlights the need to consider autoimmune causes in primary mental

A case of anti-IgLON5 disease presenting with unusual clinical features has expanded current understanding of this rare autoimmune disorder. The case was investigated in a collaborative study between Euroimmun and clinics in Lübeck and Hamburg (Germany) and published in the Journal of Neurology. What is anti-IgLON5 disease?  Anti-IgLON5 disease is a rare and poorly understood

A new case of Homer-3 autoimmunity has been described, expanding the still limited body of knowledge about this rare autoimmune cerebellar disorder. The case was reported in the Journal of Neuroimmunology. What’s known so far To date, only 15 cases of Homer-3 autoantibody-associated disease have been described in the literature. The clinical phenotype in these