Science

Anti-PLA2R: a serological marker for primary membranous nephropathy

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The discovery of autoantibodies against the phospholipase A2 receptor 1 (PLA2R) is considered a milestone in nephrology research. They are the first described serological marker for primary membranous nephropathy. Their value in membranous nephropathy diagnostics is the subject of many recent publications. Primary and secondary membranous nephropathy: differential diagnosis essential Membranous nephropathy is the major cause of nephrotic syndrome in […]

Science

New biomarker for acute Lyme neuroborreliosis

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Diagnosis of acute Lyme neuroborreliosis Since 2005, the chemotactic cytokine (chemokine) CXCL13 has been considered a potential biomarker for acute Lyme neuroborreliosis [1, 2]. Lyme neuroborreliosis is the neurological manifestation of tick-borne Lyme disease which is caused by the spirochete Borrelia burgdorferi sensu lato and frequently occurs in the northern hemisphere. Symptomes of Lyme neuroborreliosis include inflammation of the central nervous system

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