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Updated COVID-19 XBB.1.5 vaccines elicit strong immune responses to new SARS-CoV-2 variants

Two new studies on SARS-CoV-2 vaccine immune responses suggest that the XBB.1.5-containing mRNA vaccines most likely increase protection against COVID-19 caused by currently circulating XBB variants and the emerging BA.2.86 variant in healthy persons and in patients on haemodialysis. The studies build on collaborative work between the Hannover Medical School, Germany and EUROIMMUN and were […]

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Omicron-induced T- and B-cell immunity in vaccinated and naïve individuals

A recent study has demonstrated substantial differences in SARS-CoV-2 immunity after Omicron infection in triple-COVID-19-vaccinated and antigen-naïve individuals, which may influence cross-protection against future variants. The study was performed as part of a collaboration between the Hannover Medical School, Germany and EUROIMMUN. Omicron variants are B-cell immune escape variants of SARS-CoV-2 that elude the defence

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Computer-aided classification of IIF patterns in autoimmune dermatoses

Deep neural networks incorporating segmentation provide highly accurate classification of immunofluorescence patterns on the tissue substrates esophagus and salt-split skin for detection of autoimmune bullous dermatoses (AIBD). A recently published study in collaboration with researchers at the Department of Dermatology and Lübeck Institute of Experimental Dermatology of the University of Lübeck, Germany describes the development

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Recombinant ELISAs increase efficiency of CMV serodiagnosis in pregnant women

EUROIMMUN ELISAs based on recombinant antigens p52 (IgM) and glycoprotein B (IgG) from cytomegalovirus (CMV) provided a higher rate of conclusive results in first-line testing of samples from pregnant women than lysate-based assays. A recombinant testing strategy could thus help to reduce the number of analyses required for routine CMV screening during pregnancy. These are

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