With passion for rheumatology! Recently, three new fluorescence patterns were added to the classification tree of the International Consensus on Antinuclear Antibody Patterns (ICAP)1. ICAP is an initiative of international scientists with the goal of evaluating the large number of ANA patterns in a standardised way. ANA (antinuclear antibodies) are biomarkers for different autoimmune diseases, […]
With passion for rheumatology! Systemic autoimmune rheumatic diseases encompass a wide range of different inflammatory joint, tissue and vascular diseases, such as rheumatoid arthritis, systemic lupus erythematosus and systemic sclerosis. They are diagnosed on the clinical history, imaging techniques, and serological tests. Antibody detection is a useful diagnostic tool and can provide essential information for
Myasthenia gravis (MG) is an autoimmune-mediated myasthenic disorder with the main symptom of exertion-related muscle weakness. The disease results from functional loss of the nicotinic acetylcholine receptors (AChR) at the motor end plate due to attacks of different autoantibodies (AAb). Autoantibodies against nicotinic AChR are detected in around 80% of MG patients. AAb against muscle-specific
With passion for rheumatology! Autoantibody testing is becoming increasingly important in rheumatological diagnostics. It delivers crucial information for differential diagnostics and sometimes even allows prediction of the disease progression or helps in the choice of therapy. Before diagnostic use, all serological tests undergo thorough investigation. They are only approved when they meet the respective criteria.
With passion for rheumatology! Indirect immunofluorescence assays (IFAs) such as for anti-nuclear antibody (ANA) testing are an important diagnostic tool in rheumatology. However, manual processing and evaluation of IFAs requires trained professionals and a lot of time. With innovative solutions and modern technologies, EUROIMMUN makes an important contribution to continuous development in immunofluorescence diagnostics and
