Uromodulin is a kidney-specific glycoprotein, which is exclusively expressed by the epithelial cells of the ascending limb of loop of Henle (TAL cells) and secreted into the urine. There, it is the quantitatively most significant protein. Additionally, secretion of small quantities of uromodulin into the interstitium was described. In this way the proteins gets into […]
A large cross-sectional serostudy of blood donors in Saudi Arabia has revealed a significant number of subclinical infections with Middle East respiratory syndrome coronavirus (MERS), which pose a likely source of infection in previously unexplained outbreaks of MERS. Notably, the prevalence of antibodies against MERS coronavirus (MERS-CoV) was significantly higher in persons with regular exposure
Spring is coming and you can tell: the sun is up earlier in the morning, the birds are singing, early bloomers can be seen in the gardens and by the wayside, and, another sure sign, people who are allergic to pollen start sneezing and sniffling. Even experts are unable to explain why some people develop
Vitamin D is a fascinating molecule. In the body it is involved in a multitude of biological processes, and current research is constantly uncovering new associations between vitamin D deficiency and severe disease. The connection between vitamin D and neurodegenerative diseases such as Alzheimer’s disease and other forms of dementia has been the subject of
A, B, C, D, E, K … these are the designations of vitamins that are considered essential for humans. They must be available in sufficient amounts in the body to sustain vital functions. One of these vitamins, vitamin D, has been in the limelight scientifically for several years. An adult needs around 20 µg of
