Science

Excellent performance of the automated CLIFT evaluation by the “EUROPattern Suite”

Antibodies against double stranded DNA (anti-dsDNA) are immunological indicators for systemic lupus erythematosus (SLE), a severe rheumatic autoimmune disease. According to the recommendations of the American College of Rheumatology, their detection constitutes an important criterion for the diagnosis of the disease [1]. Among the commonly applied test systems, indirect immunofluorescence on the flagellate Crithidia luciliae […]

Science

Autoantibody diagnostics in autoimmune nephropathies

Autoimmune-mediated damage to the kidneys can be triggered by autoantibodies directed against renal proteins, as in the case of primary membranous nephropathy (MN) or Goodpasture syndrome, or may occur secondary as part of the wide-reaching effects of systemic autoimmune diseases such as vasculitis or systemic lupus erythematosus (SLE). The detection of specific autoantibodies in patient

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